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Acinetobacter baumannii:
A. baumannii "is a prime example of a mismatch between unmet medical need and the current antimicrobial research and development pipeline," according to the Clinical Infectious Diseases article. The bacterium is a growing cause of hospital-acquired pneumonia. Mortality rates range from 20 to 50 percent. The number and hardiness of drug-resistant strains are growing. Soldiers are also returning from Iraq and Afghanistan with cases of highly resistant Acinetobacter wound infections. Doctors have been forced to resort to an old drug, colistin, which had previously been abandoned as too toxic. But only one new drug is on the horizon to treat Acinetobacter infections, and it is considered to be too toxic for children.  |
Facility
TransPharm Preclinical Solutions is an AAALAC accredited facility located on a scenic wooded fifteen acre setting in Jackson County, Michigan. The company is housed in an interconnected 6,200 sq. ft. complex of buildings including a 1,000 sq. ft. vivarium with an attending 230 sq. ft. surgical suite. The vivarium is a negative pressured facility equipped with bioBubble® clean rooms. The facility is designed to handle all BSL II Applications. General laboratory work is conducted in a 1,700 sq. ft. wet lab area equipped to handle all microbiological procedures and analyses. This work area includes biological containment hoods, sterile work stations, chemical use hoods, and general lab work benches. The entire facility is backed up by a 90,000 watt generator to avoid any catastrophic loss of data. The administrative area includes 1,220 sq. ft. of office space complete with video-link conference room.  
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